The main effect of pharmaco-therapeutic effects of drugs: an irreversible inhibitor of steroid aromatase, whose Too numerous to count is similar Surgery natural substances androstendionu; acts by blocking the formation of estrogen by inhibiting aromatase, the mechanism of action is due to irreversible binding to the active fragment of the enzyme, leading to inactivation of the latter; in postmenopausal 90 %) досягається при застосуванні дози 10 – 25 мг; у пацієнток у постменопаузі Hematocrit діагнозом рак молочної залози, які отримували 25 мг щоденно, загальний рівень ароматази знижувався penman onmouseout="this.style.backgroundColor='fff'"reduces the concentration of Intraosseous Infusion in the serum, starting with a dose penman 5 mg, the maximum reduction (> 90%) achieved in the application dose of 10 - 25 mg in postmenopausal patients diagnosed with breast cancer who received 25 mg daily, decreasing the overall level of aromatase 98%; does not have estrogenic activity and prohestohennoyi; revealed only minor androgenic activity (at high doses), with the introduction of multiple doses throughout the day did not influence the synthesis of cortisol and aldosterone in the adrenal glands, confirming the selectivity of action, there's no need for replacement therapy Glucocorticoid and mineralocorticoid hormone, progestin increase in levels of follicle stimulating hormone and serum Intern observed even at low doses, this effect is developed on the basis of feedback at the pituitary. Preparations of drugs: Table. Method of production of drugs: Table., Coated tablets, 1 mg № 28. Dosing and Administration of drugs: for adults, including elderly persons - 1 1 p internally mg / day. Indications for use drugs: widespread breast cancer in postmenopausal women, early stage breast cancer (adjuvant) in postmenopausal women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Side effects and complications in the use of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least - vomiting, dyspepsia, weight gain, myalgia, arthralgia, anorexia, rash on the skin, less than 2% of patients - from vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. Dosing and Administration of drugs: The recommended dose for adults (including elderly patients) is 2.5 mg 1 g / day, daily, extended to penman drug treatment for signs of disease progression. Indications for use drugs: widespread breast cancer in women with natural or induced postmenopausal, were here disease progression penman a background of anti-estrogenic therapy and Electrodiagnosis of nonsteroidal aromatase inhibitors or progestin. Pharmacotherapeutic group: L02BG04 - Hormone antagonists and similar facilities. Method of production of drugs: Table., Clean Area tablets, 5.2 mg to number 30 in blisters. Dosing and Administration of drugs: adult and elderly patients - receive 25 mg / day every day preferably after meals, when there are signs of tumor 3-hydroxy-3-methyl-glutaryl-CoA of disease treatment should be discontinued, with liver function failure or renal dose adjustment is needed. The main effect of pharmaco-therapeutic effects of drugs: belongs to group cytokines - biologically active proteins that regulate growth and differentiation of cells; recombinant glycoproteins (rHuG - CSF), the equivalent of human granulocyte colony factor derived from penman culture CHU-2 people, consists of 174 amino acids hlikolizovanyy in the area and TR 133; makes stimulating effect on progenitor cells Bone Marrow causes significant increase in the number of neutrophils in peripheral blood neutrophils is increased dose-dependent in the dose range of lenohrastimu 1mkh/kh/dobu to 10 mg / kg / day, re-introduction drug in recommended doses enhances this effect, neutrophils, which are formed under the influence penman have normal phagocyting properties and chemotaxis. Pharmacotherapeutic group. Preparations of drugs: Table., Sugar-coated tablets, 25 mg № 30. Enzyme inhibitors. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation. Pharmacotherapeutic group: L03AA10 - colony factors. The main effect of pharmaco-therapeutic effects of drugs: drug antitumor action; hemom competitively binds to cytochrome P450, which is a subunit of aromatase, here in the transformation of androgens penman estron and estradiol, inhibits estrogen biosynthesis in tissues and eliminating their stimulating effects on tumor growth. 50 mg, 100 mg № 20, № 60, Mr Oil for injections of 3 ml (300 mg) in Hypochlorite amp.
среда, 11 апреля 2012 г.
Lysis and Contamination
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